Propranolol is classified as a beta blocker. It is sold in the United States under the brand name Inderal. When combined with the diuretic, hydrochlorothiazide, it is sold under the brand name Inderide. Propranolol also is produced as a generic product by a number of generic manufacturers. Propranolol is approved by the Food and Drug Administration FDA for the treatment of hypertension high blood pressureangina, certain types of cardiac arrhythmias, certain types of cardiac output diseases, a sympathetic nervous system disorder known as pheochromocytoma, hyperthyroid conditions, migraine, heart attack, and tremors of a variety of origins.
It is also used on occasion for the treatment of medication-induced movement disorders caused by antipsychotic drugs and certain anxiety states in people suffering from a specific form of social phobia. Beta blockerssuch as propanolol, are not useful for people with general social phobia who are anxious in most social situations; instead, propanolol may be useful for people who are anxious about specific performance situations, such as presenting a speech before an audience.
Propranolol falls into the broad pharmacologic category known as beta blockers. Beta blockers block specific sites in the central central nervous system and inderal system known as beta-adrenergic receptor sites. When these sites are blocked, heart rate and blood pressure are reduced and patients become less anxious. Because of this, propranolol is useful in treating chest pain, high blood pressure, and excessive nervousness.
Unfortunately, propranolol often makes breathing disorders, such as asthma, worse because it tends to constrict breathing passages and sometimes causes fluid to build up in the lungs if it excessively depresses the heart. In the treatment of anxiety, propranolol is usually not administered on a chronic basis but, rather, prior to stressful events such as public speaking or acting.
In the treatment of certain types of tremors, especially tremors secondary to a drug, and movement disorders secondary to antipsychotic therapy, propranolol is administered throughout the day in divided doses. Propranolol is available in, and mg tablets; in long-acting capsules; and an injectable form containing 1 mg per mL. It is also combined with the diuretic hydrochlorothiazide in tablets and extended-release capsules.
For the treatment of performance anxiety or stage fright, a single dose of 10—40 mg may be administered 20—30 minutes before the event. For the treatment of tremors, especially tremors secondary to lithium, doses range from 20 to mg per day administered in two or three divided doses. For the treatment of movement disorders secondary to antipsychotic drug therapy, doses range from 10 to 30 mg three times daily.
Precautions should be taken when administering propranolol in the following situations:. The following side effects have been observed with propranolol. Most have been mild and transient temporary and rarely require the withdrawal of therapy:. See also Alcohol and related disorders. Nursing Drug Handbook, central nervous system and inderal. Lippincott, Williams and Wilkins, Thomas, central nervous system and inderal, Clayton, MD, editor.
Definition Propranolol is classified as a beta blocker. Description Propranolol falls into the broad pharmacologic category known as beta blockers. Recommended dosage For the treatment of performance anxiety or stage fright, a single dose of 10—40 mg may be administered 20—30 minutes before the event. Precautions Precautions should be taken when administering propranolol in the following situations: Side effects The following side effects have been observed with propranolol, central nervous system and inderal.
Most have been mild and transient temporary and rarely require the withdrawal of therapy: Interactions When drugs that deplete the body of epinephrine and norepinephrine such as reserpine and guanethidine are taken with propranolol, interactions have been reported.
Some of these interactions decapeptyl and breast cancer and fda Drugs known as calcium channel blockers may decrease the pumping ability of the heart and lead to the development of cardiac arrhythmias. Nonsteroidal anti-inflammatory agents i. Aluminum hydroxide antacids greatly reduce the rate of intestinal absorption of propranolol. Alcohol slows the rate of diane 35 and yasmin absorption.
Interactions have also been reported with phenytoin, rifampin, phenobarbital, chlorpromazinelidocaine, thyroxin, cimetidine, and theophylline. Other articles you might like: Also read article about Propranolol from Wikipedia.
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