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Dhea and cancer

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This article is from the book by Timothy J. American Academy of Anti-Aging Medicine. American Dhea and cancer for Advancement in Medicine. A growing dhea and cancer of research suggests that DHEA can prevent or reverse the diseases that anti-aging experts have identified as the most prominent markers of accelerated aging: There is no question that DHEA extends the life spans of animals and holds promise as a defense against the degenerative diseases of aging.

But can the hormone actually extend human life span? While the research literature strongly supports this claim, it remains unproven. The definitive diabetes and adhesive capsulitis should come soon.

Formerly relegated to a position of minor importance by the scientific establishment, dhea and cancer, DHEA has become the subject of intense scrutiny. These and other major agencies are investigating DHEA as dhea and cancer potential treatment for chronic fatigue syndrome, depression, Epstein-Barr virus, dhea and cancer, lupus and other autoimmune diseases, menopausal symptoms, osteoporosis, and even AIDS.

What can the average healthy person expect from DHEA? Other benefits include enhanced immunity stronger resistance to colds, flu, and blindness and diabetes like and lower cholesterol.

Your adrenal glands are responsible for manufacturing DHEA. Actually, dhea and cancer, the cascade of adrenal hormones starts with cholesterol, from which the brain hormone pregnenolone is made. Pregnenolone is then transformed into DHEA.

And DHEA serves as the raw material from which all other important adrenal hormones--including the sex hormones estrogen, progesterone, and testosterone and the stress hormone cortisol--are synthesized. DHEA is the most abundant hormone in your dhea and cancer. But production peaks at around age From then on, your DHEA level decreases with age.

By the time you reach 40, your body makes about half as much DHEA as it used to. By 65, output drops to 10 to 20 percent of optimum; by age 80, it plummets to less than 5 percent of optimum. Because DHEA has such broad-spectrum effects, declining production makes itself known in every system, every organ, and every tissue of your body.

If levels of DHEA decline with age, can replacing the hormone reverse aging in humans? Nobody knows for sure. In studies, laboratory animals given DHEA supplements live up to 50 percent longer than normal.

DHEA levels in men between the ages of 50 and 79 were tracked for 12 years in a study by noted hormone researcher Elizabeth Barrett-Connor, M. The study found a close correlation between higher DHEA levels and reduced risk of death from all causes. The men who survived had three times the DHEA levels of the men who died.

Research has pinpointed low DHEA levels as a marker for many degenerative diseases and accelerated aging. Scientists now have proof that DHEA: How could any substance that protects us from virtually every major degenerative disease not protect us from aging as well? Living Better Than Ever. Whether or not DHEA extends life span, it undoubtedly improves quality of life. Most people dhea and cancer take DHEA do so because the hormone helps them deal better with stress, gives them more pizzazz, and makes them feel young again, dhea and cancer.

My patients on DHEA almost invariably report that they just plain feel better. This is not a placebo effect. Research has shown that DHEA levels in the bloodstream correlate highly with general health and vitality, sense of well-being, and increased stress tolerance.

Inthe Journal of Clinical Endocrinology and Metabolism published the first placebo-controlled dhea and cancer study examining the therapeutic effects of DHEA replacement therapy. The DHEA-takers had more energy, slept better, and handled stress better than the placebo-takers. The researchers concluded that "DHEA will improve the quality of life over dhea and cancer longer period and will dhea and cancer some of the unpleasant effects of aging, such dhea and cancer fatigue and muscle weakness.

Sixty-seven percent of the men and 84 percent of the women reported dhea and cancer in energy, sleep, mood, feelings of relaxation, and ability to handle stress--overall, a remarkable increase in subjective experience of physical and psychological well-being. Does DHEA rejuvenate immune function? It boosts antibody production; enhances the activity of monocytes, immune cells that attack cancer cells and viruses; activates natural killer cells, dhea and cancer, immune cells that attack and destroy viruses and other foreign invaders; and maximizes the anti-cancer function of immune cells known as T lymphocytes.

Dhea and cancer aging laboratory animals, DHEA restores youthful levels of cytokines immune chemicals involved in protection and healing and reduces the production of autoantibodies antibodies that attack healthy tissues. When administered concurrently with a flu vaccine, DHEA dramatically improved the effectiveness of the vaccine in aging mice and in older humans.

Remember, heightened immunity translates directly into protection against oxidation, which in turn translates directly into protection against degenerative disease, dhea and cancer. So anything that strengthens your immune system also has the capacity to lengthen life, dhea and cancer.

Immune deterioration with age is accompanied by increased incidence of atherosclerosis, autoimmune diseases, cancer, cataracts, and infections--all evidence of accelerated aging.

After measuring baseline immune parameters in healthy older men average age 63Dr. Yen put the men on a program of 50 milligrams of DHEA per day. After 20 weeks, the men showed dramatic improvement in all markers of immune function, including an average of 45 percent increases in monocytes, 29 percent increases in antibody-making B lymphocytes, 20 percent increases in T lymphocyte activation, 40 percent increases in T lymphocyte anti-cancer response, and 22 to 37 percent increases in natural killer cells.

Perhaps most significant of all, dhea and cancer, DHEA increases production of insulin-like growth factor-1 IGF-1a hormonelike molecule that is used to measure levels of another potent anti-aging compound called human growth hormone. Stopping Stress in Its Tracks. DHEA protects your body from the hormone cortisol and the stress that triggers its production. Like DHEA, dhea and cancer, cortisol is secreted by the adrenal glands. People under chronic stress have high cortisol levels unless their adrenal glands have already burned out, in which case their cortisol levels are low.

The presence dhea and cancer too much cortisol leads to age-accelerating damage. As stress accumulates over decades, cortisol levels tend to rise as well.

Many people over age 40 have elevated cortisol. DHEA and cortisol have an inverse, or adversarial, relationship. Mending a Broken Heart. Several studies examining the role of DHEA in dhea and cancer disease have produced intriguing findings.

Research has shown that depleted DHEA is a more accurate predictor of heart attack than elevated cholesterol.

DHEA levels were significantly lower dhea and cancer men who died of heart attacks than in men who were healthy. DHEA level was shown to correlate with the degree of atherosclerosis in men and women undergoing coronary angiography, in a study by David Herrington, M.

He found that as DHEA levels went up, coronary artery disease as measured by the frequency and severity of arterial lesions went down. A follow-up study showed that the degree of development of atherosclerosis in 63 heart transplant patients was inversely correlated with DHEA levels.

In people undergoing angioplasty a procedure in which a balloon is used to open a clogged blood vesselDHEA reduced the rate of restenosis--a treated vessel closes off again--from 68 percent to 28 percent. In healthy males given a clot-promoting substance arachidonic acid, found in abundance in meatDHEA dhea and cancer an increase in clotting.

An increased tendency to clot is a risk factor for heart attack and stroke. In men, DHEA lowered total cholesterol and "bad" low-density lipoprotein cholesterol better than and more safely than the "statin" drugs such as clofibrate and gemfibrozil, dhea and cancer.

DHEA is also nontoxic. Animal studies are producing similar promising results. When researchers gave DHEA to rabbits with atherosclerotic arteries, dhea and cancer, the hormone produced a 50 percent decline in arterial plaques. The bottom line in all of this: Can DHEA prevent cancer?

Low DHEA predicts breast cancer more accurately than any other known marker. Women with breast cancer consistently have lower-than-normal DHEA readings. DHEA may help protect against breast cancer by inhibiting glucosephosphate dehydrogenase, an enzyme required for cancer growth. Also, because DHEA has antioxidant properties, the hormone probably defends against free radical cancer initiators.

In animal studies, DHEA has provided dramatic protection against tumors of the breasts, colon, liver, lungs, lymphatic vessels, prostate, and skin. This is especially true with DHEA because very little of the hormone is delta airlines and diabetes in the bloodstreams of rodents. So despite a general feeling among anti-aging experts that DHEA may well inhibit cancer formation, the jury remains out on the DHEA-cancer link--at least for the time being.

Good to Your Bones. Osteoporosis is like a football game. Make do with a weak offense, and the opposing team will push you back for a serious loss, dhea and cancer. Certain dietary and lifestyle factors give the opponent a distinct advantage: You can retain control of the ball by recruiting the following players for your bone-building team: Among the anti-aging hormones, DHEA stands out as a multitalented star with amazing ways of outsmarting osteoporosis.

DHEA is the only hormone that can both inhibit bone breakdown and stimulate bone formation. Plus, DHEA is a precursor to estrogen, progesterone, and testosterone, all of which prevent bone loss in their own rights. Bone cells dhea and cancer DHEA to estrone, a type of estrogen that in turn increases the activity of bone-making cells called osteoblasts.

Japanese researchers found a positive correlation between DHEA dhea and cancer and bone density in women over age As DHEA levels decline with age, osteoporosis may appear.

People with osteoporosis have significantly lower DHEA levels than people without the disease. When osteoporotic lab animals are given DHEA, their bones remineralize--that is, their bones become stronger. Although human studies have yet to be done, dhea and cancer, DHEA supplementation would in all likelihood increase our bone density as well. Medicine for the Mind. You can say you read it here first.


Dhea and cancer