Iron-drug interactions of clinical significance may occur in many patients and involve a large number of aspartame and arthritis. Concurrent ingestion of iron causes marked decreases in the bioavailability of a number of drugs. The affected drugs, tetracycline, tetracycline derivatives doxycycline, methacycline and oxytetracyclinepenicillamine, methyldopa, levodopa, carbidopa and ciprofloxacin have diverse chemical structures and clinical effects.
The major mechanism of these drug interactions is the formation of iron-drug complexes chelation or binding of iron by the involved drug. A large number of other important and commonly used doxycycline and iron such as thyroxine, captopril and folic acid have been demonstrated to form stable complexes with iron.
There is little known about the effects of doxycycline and iron therapy with iron supplements for most of the drugs. National Center for Biotechnology Informationdoxycycline and iron, U. Br J Clin Pharmacol. This article has been cited by other articles in PMC, doxycycline and iron. Abstract Iron-drug interactions of clinical significance may occur in many patients and involve a large number of therapies, doxycycline and iron.
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Chem Pharm Bull Tokyo Dec; 33 Inhibition of intestinal iron transport induced by tetracycline. Spectrophotometric determination of trace amounts of iron III with norfloxacin as complexing reagent. The interaction of warfarin with antacid constituents in the gut.
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